8af983e4-e97d-4c07-a34d-753243fa283b English ISO/IEC 8859-1 (also known as Latin 1) dataset dataset NERC EDS Environmental Information Data Centre Lancaster Environment Centre, Library Avenue, Bailrigg Lancaster LA1 4AP UK info@eidc.ac.uk https://eidc.ac.uk/ EIDC website The Environmental Information Data Centre (EIDC) is the UK's national data centre for terrestrial and freshwater sciences. information pointOfContact 2025-11-13T16:17:28 UK GEMINI 2.3 OSGB 1936 / British National Grid Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment 2014-08-01 publication 2009-11-03 creation 1406898956642 CEH:EIDC: https://catalogue.ceh.ac.uk/id/8af983e4-e97d-4c07-a34d-753243fa283b 10.5285/8af983e4-e97d-4c07-a34d-753243fa283b doi: Singer, A.C., Järhult, J.D., Grabic, R., Khan, G.A., Lindberg, R.H., Fedorova, G., Fick, J., Bowes, M.J., Olsen, B., Söderström, H. (2014). Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment. NERC Environmental Information Data Centre 10.5285/8af983e4-e97d-4c07-a34d-753243fa283b This dataset contains the concentration of eleven antibiotics (trimethoprim, oxytetracycline, ciprofloxacin, azithromycin, cefotaxime, doxycycline, sulfamethoxazole, erythromycin, clarithromycin, ofloxacin, norfloxacin), three decongestants (naphazoline, oxymetazoline, xylometazoline) and the antiviral drug oseltamivir's active metabolite, oseltamivir carboxylate, measured at 21 locations within the River Thames catchment in England. The measurements were taken weekly during November 2009, once in March 2010 and once in May 2011, with the aim to quantify pharmaceutical usage during the influenza pandemic of 2009 and how this compares to inter-pandemic drug use. River samples were acquired by grab samples in glass jars and analysed by liquid chromatography tandem mass spectrometry (LC MS). Two wastewater treatment plants (WWTPs) in southern England (Benson and Oxford) were also sampled during the peak of the second wave of the 2009 influenza A[H1N1]pdm09 pandemic (10-11 November 2009) and on 15 May 2011 using an automated sampler set to acquired hourly (time proportional) samples from the influent and effluent of the WWTPs. The WWTPs are the source for all the drugs found in the river, hence, these were studied to understand the differential fate of the analytes in the two very different WWTPs. Flows for the WWTP and River sampling locations are presented for each of the sampling times to allow for determining hourly loads for the WWTP and daily loads for the river. Full details about this dataset can be found at https://doi.org/10.5285/8af983e4-e97d-4c07-a34d-753243fa283b Singer, A. UK Centre for Ecology & Hydrology enquiries@ceh.ac.uk pointOfContact Singer, A.C. Centre for Ecology & Hydrology enquiries@ceh.ac.uk https://orcid.org/0000-0003-4705-6063 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Järhult, J.D. Uppsala University enquiries@ceh.ac.uk https://orcid.org/0000-0002-7075-1059 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Grabic, R. University of South Bohemia in Ceske Budejovice enquiries@ceh.ac.uk https://orcid.org/0000-0002-0935-2075 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Khan, G.A. Umeå University enquiries@ceh.ac.uk author Lindberg, R.H. Umeå University enquiries@ceh.ac.uk https://orcid.org/0000-0001-5352-0091 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Fedorova, G. University of South Bohemia in Ceske Budejovice enquiries@ceh.ac.uk https://orcid.org/0000-0001-5492-7459 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Fick, J. Umeå University enquiries@ceh.ac.uk https://orcid.org/0000-0002-3949-7371 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Bowes, M.J. Centre for Ecology & Hydrology enquiries@ceh.ac.uk https://orcid.org/0000-0002-0673-1934 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author Olsen, B. Uppsala University enquiries@ceh.ac.uk author Söderström, H. Umeå University enquiries@ceh.ac.uk https://orcid.org/0000-0002-0842-3409 ORCID record ORCID is an open, non-profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. information author NERC EDS Environmental Information Data Centre info@eidc.ac.uk custodian NERC Environmental Information Data Centre info@eidc.ac.uk publisher UK Centre for Ecology & Hydrology enquiries@ceh.ac.uk owner notPlanned Hydrography theme GEMET - INSPIRE themes, version 1.0 2008-06-01 publication pandemics antibiotic waste water treatment plant river epidemiology GEMET - Concepts, version 4.1.3 2019-01-28 creation Water quality River Thames catchment (UK) influenza antiviral decongestant River Thames Benson Sewage Works Oxford Sewage Works otherRestrictions no limitations otherRestrictions This resource is made available under the terms of the Open Government Licence otherRestrictions © UK Centre for Ecology & Hydrology otherRestrictions If you reuse this data, you should cite: Singer, A.C., Järhult, J.D., Grabic, R., Khan, G.A., Lindberg, R.H., Fedorova, G., Fick, J., Bowes, M.J., Olsen, B., Söderström, H. (2014). Antiviral, antibiotics and decongestants in wastewater treatment plants and receiving rivers in the Thames catchment. NERC Environmental Information Data Centre https://doi.org/10.5285/8af983e4-e97d-4c07-a34d-753243fa283b textTable English utf8 inlandWaters 2009-11-11 2011-05-11 -2.013 -0.31 51.217 52.113 Comma-separated values (CSV) NERC EDS Environmental Information Data Centre info@eidc.ac.uk distributor https://data-package.ceh.ac.uk/data/8af983e4-e97d-4c07-a34d-753243fa283b Download the data Download a copy of this data download https://data-package.ceh.ac.uk/sd/8af983e4-e97d-4c07-a34d-753243fa283b.zip Supporting information Supporting information available to assist in re-use of this dataset. information dataset dataset Commission Regulation (EU) No 1089/2010 of 23 November 2010 implementing Directive 2007/2/EC of the European Parliament and of the Council as regards interoperability of spatial data sets and services 2010-12-08 The sampling of all analytes in the Benson and Oxford WWTP was performed during a 24-hour period spanning 10-11 November 2009. An additional 24-h sampling was initiated on May 15, 2011 from only the Benson WWTP effluent. An automated sampler was used to recover a time-proportional sample (approximately 750 ml) of influent and effluent every hour for 24 hours. Samples were aliquoted into triplicate 50-ml borosilicate glass vials with PTFE-lined caps and immediately stored at -80°C until analysis. Grab samples were acquired from the main river flow at 21 locations within the Thames catchment as part of the CEH Thames Initiative Research Platform on November 3, 11, 17, and 24, 2009, as well as on March 15, 2010 (late-pandemic period) and May 11, 2011 (inter-pandemic period). River flow data was acquired from the National River Flow Archive (http://www.ceh.ac.uk/data/nrfa/) for all locations at the closest gauging station to the sampling site. Samples were transported from the field to the laboratory in amber glass jars (250 ml) within siz hours and transferred into 50-ml borosilicate glass vials with PTFE-lined caps, in triplicate. The samples were stored at -80°C until analysis. An on-line solid phase liquid extraction/liquid chromatography-tandem mass-spectrometry (SPE/LC-MS/MS) method was used to measure the analyte levels in pre-filtered and acidified 1 mL-samples. This on-line SPE/LC-MS/MS method used has 132 been evaluated and described in detail previously: Khan GA, Lindberg R, Grabic R, Fick J (2012) The development and application of a system for simultaneously determining anti-infectives and nasal decongestants using on-line solid- phase extraction and liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal 66: 24-32.